Recent Selected Publications (Full list in CV under lab members link)

Holmes, W.R. and Grover, L.M. 2006. Quantifying the magnitude of changes in synaptic level parameters with long-term potentiation. J. Neurophysiol. 96:1478-1491.

Holmes, W.R., Ambros-Ingerson, J. and Grover L.M. 2006. Fitting experimental data to models that use morphological data from public databases. J. Comput. Neurosci. 20:349-365.

Holmes, W.R. 2005. Calcium signaling in dendritic spines. In: Modeling in the Neurosciences. G.N. Reeke, et al. (eds) CRC Press: Boca Raton, pp. 25-60.

Ambros-Ingerson, J. and Holmes, W.R. 2005. Analysis and comparison of morphological reconstructions of hippocampal field CA1 pyramidal cells. Hippocampus 15:302-315.

Li, Y. and Holmes, W.R. 2000. Comparison of CaMKinase II activation in a dendritic spine computed with deterministic and stochastic models of the NMDA synaptic conductance. Neurocomputing 32-33:1-7.

Holmes, W.R. 2000. Models of calmodulin trapping and CaM Kinase II activation in a dendritic spine. J. Comput. Neurosci. 8:65-85.

Aradi, I. and Holmes, W.R. 1999. Role of multiple calcium and calcium-dependent conductances in regulation of hippocampal dentate granule cell excitability. J. Comput. Neurosci. 6:215-235.

Holmes, W.R. and Aradi, I. 1998. Modeling the contributions of calcium channels and NMDA receptor channels to calcium current in dendritic spines. In: Computional Neuroscience: Trends in Research, 1998. J.M. Bower, editor. pp. 191-196.

Holmes, W.R. and Levy, W.B. 1997. Quantifying the role of inhibition in associative long-term potentiation in dentate granule cells with computational models. J. Neurophysiol. 78:103-116.

Holmes, W.R. 1995. Modeling the effect of glutamate diffusion and uptake on NMDA and non-NMDA receptor saturation. Biophys. J. 69(5): 1734-1747.

Recent Abstracts

Holmes, W.R and Grover, L.M., 2006. Quantifying the magnitude of changes in synaptic level parameters with LTP. Program No. 39.13. 2006 Abstract Viewer/Itinerary Planner. Atlanta, GA; Society for Neuroscience.

Ambros-Ingerson, J., Grover, L.M., and Holmes, W.R. 2006. Sensitivity parameter analysis by evolutionary search method in a hippocampal CA1 pyramidal cell model. Program No. 101.14. 2006 Abstract Viewer/Itinerary Planner. Atlanta, GA; Society for Neuroscience.

Holmes, W.R. and Grover L.M. 2006. The mechanism of LTP affects dendritic computation. CNS*2006. Edinburgh, UK

Holmes, W.R. and Grover L.M.. 2005 Fitting experimental data to models that use morphological data from public databases. CNS*2005. Madison, WI.

Ambros-Ingerson, J., Grover, L.M., and Holmes, W.R. 2005. A parameter search method for optimal matching of impulse firing waveforms from CA1 hippocampal cells. Program No.738.4. 2005 Abstract Viewer/Itinerary Planner. Washington, DC; Society for Neuroscience.

Ambros-Ingerson, J. and Holmes, W.R. 2004. Contribution of hyperpolarization-actiated (Ih) currents to the resting conductance and resting potential of hippocampal CA1 pyramidal cells Program No. 52.7. 2004 Abstract Viewer/Itinerary Planner. Washington, DC; Society for Neuroscience.

Holmes, W.R. and Zeng, S. 2004. The role of calcium signal time course on CaMKII switching behavior explored in a stochastic model of CaMKII activation in a dendritic spine. Program No. 498.2. 2004 Abstract Viewer/Itinerary Planner. Washington, DC; Society for Neuroscience.

Holmes, W.R. and Zeng, S. 2004. Stochastic model of calcium initiated reactions in a dendritic spine. CNS*04 Abstr.

Holmes, W.R., Ambros-Ingerson, J. and Grover, L.M. 2003. Modeling the magnitude of the change with LTP at individual CA1 synapses. Program No. 476.18. 2003 Abstract Viewer/Itinerary Planner. Washington, DC; Society for Neuroscience.

Ambros-Ingerson, J. and Holmes, W.R. 2003. Suitability of CA1 morphological reconstructions for computer simulations. Program No. 476.18. 2003 Abstract Viewer/Itinerary Planner. Washington, DC; Society for Neuroscience.

Holmes, W.R. and Grover, L.M. 2002. Quantifying the change at individual synapses after LTP induction in CA1. 2002 Abstracts Viewer/Itinerary Planner. Program No. 152.16. Washington DC: Society for Neuroscience. CD-ROM.

Li, Y. and Holmes, W.R. 2002. Modeling postsynaptic calmodulin stores and the effect of local calcium domains on CaMKII activation during LTP induction. 2002 Abstracts Viewer/Itinerary Planner. Program No. 150.20. Washington DC: Society for Neuroscience. CD-ROM.

Li, Y. and Holmes, W.R. 2000. CaMKinase II activation is significantly affected by spine head shape and PSD size in LTP induction. Soc. Neurosci. Abstr. 26:1903.

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